服務熱線
15201163601
-
這些資料可以幫你詳細了解ALZET滲透泵
發(fā)布時間： 2021-07-21 點擊次數(shù)： 1041次ALZET滲透泵是在片芯外包被一層聚合物構成的半透性衣膜，用激光在片劑衣膜層上開一個或多個適宜大小的釋藥小孔而制成。口服后，胃腸道內的水分通過半透膜進入片芯，因滲透壓活性物質使膜內溶液呈高滲，膜內外存在的滲透壓使水分繼續(xù)進入膜內，從而使藥物溶液或混懸的藥物從小孔泵出。常用的半透膜材料為醋酸纖維素。滲透壓活性物質起調節(jié)藥室內滲透壓的作用，其用量與零級釋藥時間長短有關，常用氯化鈉、乳糖、果糖、葡萄糖、甘露糖等。ALZET滲透泵控釋制劑主要由藥物、半透膜材料、滲透壓活性物質和推動劑組成。它的體積只有膠囊大小，可植入實驗動物皮下或腹腔內，直接或通過導管以µl/小時的速度持續(xù)準確地輸注測試藥劑。這種輸注根據(jù)所使用的泵，可以在動物清醒無束縛條件下長持續(xù)6個星期。ALZET滲透泵的使用優(yōu)點：1、ALZET滲透泵型控釋片以滲透壓為驅動力，以零級釋放動力學為釋藥特征，能夠在一定的時間范圍內以恒定的釋藥速率釋放藥物，釋藥速率一般不受釋放介質pH、攪拌速度以及胃腸蠕動、食物等因素影響，能夠在較長時間內維持恒速釋藥，減少用藥頻率。2、體內外相關性較好，可避免普通口服制劑造成的血藥濃度波動較大的現(xiàn)象，提高用藥的安全性和有效性。
產品中心
Products
-
化學試劑
Origene parkell pan-biotech PAN lexogen Lampire labtidebiotech laborator labome ABI enzolifesciences emsdiasum EtonBioscience Equitech-bio kirgen invivogen integralmolecular Instech IndoorBiotechnologies INCELL IMMUSMOL G-Biosciences IMMUNOLOGICALS idtdna IMMUNODX ILLUMINA Immunodiagnostics IBALifeSciences Hypoxyprobe Horizon Cygnus Technologies Hellobio Greiner Cell Signaling Glycobiotech Corning FST Evrogen eurofins BioFire Defense biodatacorp atlasantibodies ATCC Astartebio ArcticZymes aobious anshlabs Advanced ChemTech Advaced Cell Diagnostics AdvanDx Agar Scientific ACBR TRc polyscience Fluka Gene Bridges fortebio Biocrick Fisher bioflux biomax beckman AmericanElements MOLTOX Permagen USA Scientific Chemgenes寡核苷酸 Asuragen vmrd抗體 Thermo asusragen AmplideX toxin polyplus signagen Berry&Associates ALZET滲透泵 alzet abcr abvector SGI-DNA Goldbio Iduron Sgidna Chromsystems Coriell GE Chemgenes Matreya Streck VMRD Sigma Cerilliant Innovative Cell Technologies Diagenode Trilinkbiotech Medkoo life diagnostics Gibco Neuromab全國總代 Novus BioLegend Bethyl Toxin Technology Listlabs Seracare 寶利嘉 賽默飛 安迪生物 行業(yè)專用試劑
-
生物試劑
Biosharp Sciex Seahorse Proteintech DiaMag complementtech PeproTech hooke Nzytech Pierce pepnet pelfreez PALL ozbiosciences OXOID ORFLO ommscientific omega nanopore ncbi NexcelomBioscience Mpbio MultiSciences MyBioSource Musechem MiltenyiBiotec minerva-biolabs microspheres-nanospheres microfil microbix modiquestresearch MOBITEC mercodia merckmillipore medicago JPT kerafast Kangchen Malvern magen Kapa Macrocyclics Macherey mabtech Lucigen leica Lifespan lifesensors lifeline life-ilab Lifecore life Licor advancedchemtech Affinity Abgent Abmgood ActiveMotif Acros Acrobiosystems enzymatics epicypher Elastin elabscience Echelon eBioscience eastcoast eaglebio E&K SCIENTIFIC ekfusa duran DSHB Dharmacon DGRC Dako Cypex comptech Encorbio Jetbiofil JCRBcellbank ISOSCIENCES INVIVOCHEM iris-biotech Full Moon BioSystems GBI FormnMax Finescience Favorgen CordenPharma CIL Chromadex Clodronateliposomes Chromogenix Chiron chemservice cellvis cellutron CELLTREAT cellscript cellbiolabs cellecta cedarlane cdnisotopes carbosynth cambio calbioreagents Buchem Boston Cellron Bioworld Biowest Biotium biostatus BiosPacific Biosearch BIOplastics Biooscientific BioPAL Biomol BIOMED Biomatik bioline Biocoat Bioclone Biocision biochain華新康信 biocell Biocare BIAseparations BDpharmingen Baseclick Badrilla B2S Life Sciences Axon Medchem AXIS-SHIELD avivasysbio avidity AVES-LABS Anatrace Americanbio AlphaDiagnoesticInternational Applied Genetics Laboratories Alstem Alomone AcceGen Akina AdvancedBioMatriX Adipogen Accuratechemical Academybiomed Abcam Zymo Research Addexbio ABL Abbexa Aablocks ZeptoMetrix Tocris TAKARA Spherotech Santa Roche Nist PBL MRC Holland rd-biotech Cellgs LC-LAB Greatcell Energy Hyclone Greerlabs GlycoSyn GlycoTech EY laboratories Cayman CanSyn Bioxcell Bio－Rad Agdia Abclonal amsbio auditmicro avantilipids Alsachim HTDialysis jetPRIME Carna Biosciences FItzgerald